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Levocetirizine Dihydrochloride
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Purity:99.75%
Levocetirizine Dihydrochloride
Catalog No. T22354Cas No. 130018-87-0
Levocetirizine Dihydrochloride (Xyzal Dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Acting as an antihistaminic agent, it specifically targets the histamine H1-receptor. Levocetirizine Dihydrochloride is the R-enantiomer of Cetirizine, which gives it a higher affinity for the H1-receptor than the S-enantiomer. Due to this enhanced affinity, Levocetirizine Dihydrochloride is effective in treating allergic rhinitis and chronic idiopathic urticaria.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $43 | In Stock | |
| 25 mg | $78 | In Stock | |
| 50 mg | $133 | In Stock | |
| 100 mg | $198 | In Stock | |
| 200 mg | $297 | In Stock | |
| 500 mg | $513 | In Stock | |
| 1 g | $729 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $48 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Levocetirizine Dihydrochloride (Xyzal Dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Acting as an antihistaminic agent, it specifically targets the histamine H1-receptor. Levocetirizine Dihydrochloride is the R-enantiomer of Cetirizine, which gives it a higher affinity for the H1-receptor than the S-enantiomer. Due to this enhanced affinity, Levocetirizine Dihydrochloride is effective in treating allergic rhinitis and chronic idiopathic urticaria. |
| In vivo | Levocetirizine (0.4 mg/kg; oral administration; male Sprague-Dawley rats) yields a Cmax of 0.34 μg/mL, an AUC0-t of 3.26 μg h/mL, an AUC0-∞ of 3.67 μg h/mL, and a t1/2 of 2.34 hours in Sprague-Dawley rats[1]. |
| Alias | Xyzal Dihydrochloride, (-)-Cetirizine Dihydrochloride |
| Molecular Weight | 461.81 |
| Formula | C21H27Cl3N2O3 |
| Cas No. | 130018-87-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 90 mg/mL (194.9 mM), Sonication is recommended. DMSO: 50 mg/mL (108.27 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
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